Showing posts with label 1804. Show all posts
Showing posts with label 1804. Show all posts

Sunday, November 18, 2012

That Which We Call Rhodium By Any Other Name Would Have Been As Sweet


I introduced my favorite element back here.  Known to others since 1804, I met rhodium around 1982 or so. Rhodium drew my attention as the center of a specific type of molecule, then thought to be the closest man-made thing to an enzyme. Rhodium catalysts made unnatural amino acids such as L-DOPA. What was surprising was that it didn't make d-DOPA.

Back in the late 1970's and early 1980's asymmetric catalysis was a hot new topic. The thinking was that we could imitate nature and mimic enzymes.  Those were audacious and heady times. I can still smell how sweet it was.